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Summary of research work and implementation

 

1998 – 2001

The initial period of research concerned the frontier of electronics, metrology and medicine. During this period, was created many prototypes of devices supporting a work of both the doctor as well as the rehabilitation process. The main areas of research themes were:



  • The monitoring system objects (including patients) GPS. Under research was created application and electronic module designed to receive data from satellites needed to determine the position, responsible for the transmission of data via radio or mobile land-based system and visualization of both the traveled route as well as the current location on a digital map of the created application. The realized system has been implemented and is still distributed in The Egrotel Company.
  • Photoplethysmography multi-channel system in the diagnosis of vibration syndrome and hypothyroidism. Multi-channel detection system, transmission and mathematical curve pulse in microcirculation. The procedure gives the possibility of obtaining functional morphometric characteristics of biological objects in order to assist diagnosis.
  • Gait pathology assessment system using spatial accelerometric analysis. Uses the spatial arrangement of accelerometers, notice movement as a sequential and multi-faceted angular deviation from the arrow of gravity. Created a digital system enables accurate separation of phases, sequences and symmetry of limb movement and direct impact of these data on clinical parameters and to compare the periods before and after therapy.
  • Laser scanner driver. As part of the work executed was developed computerized control system for laser scanner, to execute the treatments laseropuncture. The prototype is equipped with a possibility of exposure of individual points in a particular sequence or plotting irregular shapes. The proposed solution enables a more flexible and precise therapy.
  • Microcomputer transcutaneous gauge concentrations of chemicals in the blood. Created microanalysis device targeted at patients with bleeding disorders, enabling the transdermal collection of blood plasma without breaching the skin and the performance of its rapid determinations of various chemical compounds. The process of plasma collection is realised using an inverted phonophoresis, which is downloading a pre set amount of plasma close to the disc gel containing the active compounds selected for the identification of substances in the blood. Electronically controlled circuitphoto densitometer determine the extinction of light passing through the colour changing disc. Phonophoresis current circuit parameters, and calibration photo densitometry integrates digital logic, whose functions are displayed on the LCD display or sent via RS 232 to PC.
  • Accelerometrical diagnostics of balance organ and monitoring the treatment process. Prototype was realized, quantitative method for measuring the deviation accelerometrical patient's body position on the Earth's gravity vector. An interactive authoring program allows the projection aberration wychwiania axis of the body to balance on a platform of support and planimetric determine the proportion of movements in time and space. The software was used in the diagnosis and quantitative evaluation of treatment effects.
  • The procedure for individual supervision in the outpatient pulmonary spirometry. Implementation of the device is based on memory cards, which are the carrier of information between the laboratory spirometry and treatments by the doctor, and a portable data file of the disease in case of sudden asthmatic attack and the need for hospitalization. Small size card in combination with relatively high information capacity proved it is advantages during a test operation at the Outpatient Rehabilitation Hospital in Cieszyn, Silesia.
  • Digital plurimetr angle in the evaluation of joint mobility. It was proposed that measuring author's program coupled with an electronic accelerometer, functioning as a motion sensor. The prototype system enables a very fast measurement range of motion in an interactive dialogue with the medical procedure without tape in the results from the computer keyboard.
  • Driver for dermatologic and laser-spot stimulation. Control system was implemented laser scanner, to enable the treatments laseropuncture. The proposed solution enables a more flexible and precise therapy
  • Automatic control of urine flow for cases with acquired bladder dysfunction. A prototype device is equipped with a Foley catheter connected to a chamber in which urine flow control solenoid valve. Valve control is realized by an electronic system that collects information from the well placed in the chamber hydrostatic sensor. Parameters of urine volume causing alarm signals and the function of emptying the bladder can be programmed by the physician. The device allows healthy, apart from conducting rehabilitation exercises control of micturition.
  • Controlling temperature gradient medicinal wraps using Peltier modules. The prototype solution procedures in question have been replaced by computer-controlled Peltier module. The device, transports heat in the direction of current flow depends on the fulfilling the role of heating and cooling. An important advantage of the proposed solution is to pool the module-plus, so you can fairly rapid temperature change procedure according to any preset curve. Proposed periodic temperature changes wraps can be used in the treatment of vascular type of neurosis syndrome Reynaud
  • Psychometric analysis of personality and talents in the procedure of the interactive dialogue with the computer. In order to facilitate and expedite the testing procedure proposed universal own program modeled on the psychometric test Mitteneckera and Tomana, who after a clinical trial has confirmed it is usefulness in the diagnosis of psychological and personnel selection processes.
  • The procedure for monitoring treatment of isotope j 131, an analysis a scintigraphic image of the thyroid. Created a system of surveillance efficacy of hyperthyroidism using isotope J131 based on comparative analysis of the distribution an emission maxima scintigraphic output and control. In contrast to the currently used an average iodine uptake measurement or visual evaluation of scintigraphic method to observe the evolution of even small foci of pathology.
  • Universal chamber for experimental laboratory preparation. Created in-one device to enable experimental work in biology, bioengineering, microbiology and medicine. The device is a summary of the experience of both engineering and construction as well as biological experiments, gained by the authors in previous experimental work.
  • An interactive computerized system for measuring the angle of flexion and extension in the hip. System for measuring the angle of flexion and extension in the hips. The device enables significant performance more objective in rheumatology and neurology tests Lasegu'a and Genslena-Menel. Measurement set consists of a hinged guide provided with an electric elevator, allowing controlled lifting and a measure of angular limb, coupled with a microcomputer.
  • The surveillance system for granulation processes in polyamide-polyurethane dressing. Copyright been proposed solution for many days, electronic surveillance granulation under the closed dressing, distinguishing between the areas and the possibility of slowly proliferating stimulate those areas of the electromagnetic field in order to accelerate the process of regeneration.
  • System for multiparameter analysis of antigenic biological objects in microbiology and immunopathology. The solution is multi-parameters matrix analyzer allows comprehensive recognition of antigenic determinants of bacterial cell walls, immunology and cancer based on changes in impedance caused by an immune reaction in individual cells and the analysis of 2d matrix using neural networks.


2001-2005


In a further stage of the study narrowed the area of medical image analysis in the wider sense.

  • Morphological analysis a iris of the eye in developing diagnostic algorithms. Through adopt TV circuit as an objective system to receive information and program segregation variable morphology of the iris, has become possible to calculate quantitative parameters in selected fields of receptor organs. A series of calibration measurements has allowed a practical test a mathematical model of the iris and start work on the standard of physiology model.
  • Computer analysis of histological and pathological diagnosis. The implementation of transmission system and image processing to allow acquisition of microscopic morphometric characteristics of biological objects in order to assist diagnosis. Mathematical treatment of the ratio picture showed the correctness of the structures to enable an accurate description of the progression a neoplastic infiltration of tissue.
  • Delimitation of human contour on infrared images. The thesis presents an original method to determine the contour of a man by a photo thermograph. This method compared with other similar methods of image processing is easy to implement and the results are reliable. The method is especially needed where for reasons of anatomical and / or the patient's physiological symmetrical setting the camera is impossible
  • The procedure for monitoring the evolution of inflammatory and degenerative diseases of the sacroiliac joints. Preparation of the linear model of the optical density distribution of the articular space in the X-ray images in normal joints and assessment of derogation from the results of similar analysis conducted in ponds during inflammation. Mathematical determination of indicators deviations from the model of physiology at the suspicion of inflammatory lesions may provide additional diagnostic criteria for changes in the sacroiliac joints.



2004 – present


In the last stage of the research the was realised some specific profile of subjects related to the processing of medical images:

Scoliosis (2004.2005)

  • Scalar approximation to the problem of diagnosis of lateral spinal curvatures. The was developed software for the delimitation of the spine by a photo thermography scalar approximation using the method.
  • Homogeneity as a measure of the features in the infrared temperature distributions. It proposes a new approach to the analysis of measurement point distribution of the harvest occurring in the infrared measurements.
  • A simplified analysis of thermal image of the spine in scoliosis diagnostic.
  • Accuracy evaluation of temperature measurement based on the surrounding paraspinal infrared images.
  • Adoption of thermography to the evaluation exercise in patients with idiopathic scoliosis
  • Computer analysis of thermal images of the spine pathology in children
  • Adoption of thermography in patients with various diseases of the spine. Presents an analysis of temperature distributions paraspinal area in children and adolescents with idiopathic scoliosis.
  • Adoption of decomposition to the squarely tree analysis temperature distributions in the diagnosis of scoliosis. The was attempted to use square-tree decomposition to extract based on infrared images of patients with spine disorders.
  • The use of methods of identification of objects in the infrared studies of patients with spinal curvatures.
  • Adoption of thermography for the selection exercise in idiopathic lateral curvature of the spine.


Three-dimensional positioning of the body (2006, 2007)

  • Computer aided image analysis and processing based on automated medical diagnosis
  • Automation of measurement on digital images as applied to photogrammetric system for three-dimensional positioning of the body for the purpose of rehabilitation.
  • Item location of individual organs based on previously identified markers.
  • Detection of eye pupils
  • Performance of selected types of neural networks are used to detect the position of the patient's eye

 

Analysis of microtubules (2005.2006)

  • Angle variation analysis of inclination a microtubules
  • 3D modelling of growth and cell division in root meristem shoot
  • Advanced methods of slope analysis of microtubules
  • Analysis of microtubule orientation using image processing methods.

 

Analysis of cellular structures (2005.2006)

  • Segmentation of cell structures
  • The cell structures segmentation with the using of decision trees,
  • The photometric analysis of selected cell Structures,

 

Analysis of thermal images of headache (2004 - 2006)

  • Headache diagnosis based on the sequence of thermal images,

Analysis of the tomographic images of the eye

  • The implementation of an algorithm designed to detect intermediate layers retina (located between the inner boundary layer of the retina and the layer of dye).
  • The was created an algorithm that detects internal boundary of the retinal layers and pigment layer.
  • Comparison of known and developed algorithms for analysis of the layers visible on the tomographic image with the rigor evaluation of 3D reconstruction and measurement of the thickness of the layers.